<b>Gene expression in trigeminal ganglion neurons </b><b>in temporomandibular joint inflamed rats </b>
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چکیده
منابع مشابه
Temporomandibular joint inflammation potentiates the excitability of trigeminal root ganglion neurons innervating the facial skin in rats.
The aim of this study was to test the hypothesis that temporomandibular joint (TMJ) inflammation alters the excitability of trigeminal root ganglion (TRG) neurons innervating the facial skin, by using behavioral, electrophysiological, molecular, and immunohistochemical approaches. Complete Freund's adjuvant (CFA) was injected into the rat TMJ to produce inflammation. The threshold for escape fr...
متن کاملGanglion of the temporomandibular joint.
falls into the third category of CMC patients. However , longitudinal studies by Valdimarsson et al.4 suggest that some patients may move between Types III and IV and that these two groups could belong to a spectrum, the position of the patient within this spectrum being determined by factors such as fungal virulence or antigenic load. The management of patients with CMC involves both the ident...
متن کاملMechanotransduction of Trigeminal Ganglion Neurons
23 To address mechanoreceptive roles of trigeminal ganglion (TG) nerve endings in the 24 inner walls of rat anterior eye chambers, we investigated the mechanotransduction 25 process and mechanosensitive (MS) channel on somata of TG neurons innervating this 26 area in vitro. Rat TG neurons innervating inner walls of anterior chambers were labeled 27 by anterior chamber injection of 1,1'-Dilinole...
متن کاملTemporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion.
Temporomandibular joint disorder (TMJD) is known for its mastication-associated pain. TMJD is medically relevant because of its prevalence, severity, chronicity, the therapy-refractoriness of its pain, and its largely elusive pathogenesis. Against this background, we sought to investigate the pathogenetic contributions of the calcium-permeable TRPV4 ion channel, robustly expressed in the trigem...
متن کاملExpression of MMP-2 and MMP-9 in the rat trigeminal ganglion during the development of temporomandibular joint inflammation
Orofacial pain is a prevalent symptom in modern society. Some musculoskeletal orofacial pain is caused by temporomandibular disorders (TMDs). This condition has a multi-factorial etiology, including emotional factors and alteration of the masticator muscle and temporomandibular joints (TMJs). TMJ inflammation is considered to be a cause of pain in patients with TMD. Extracellular proteolytic en...
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ژورنال
عنوان ژورنال: PAIN RESEARCH
سال: 2009
ISSN: 0915-8588,2187-4697
DOI: 10.11154/pain.24.147